Nicotine polacrilex, also known as nicotine resin complex, consists of nicotine bound to an ion-exchange resin called polacrilex. This structure allows for controlled release of nicotine when chewed or sucked. The resin matrix slowly releases nicotine into the oral cavity, facilitating absorption through the oral mucosa. The chemical bonding between nicotine and polacrilex prevents rapid nicotine release, reducing the urge to smoke. Nicotine polacrilex is commonly used in nicotine replacement therapy products like nicotine gum and lozenges to aid smoking cessation. Its slow-release mechanism mimics the gradual nicotine delivery of smoking, helping users manage withdrawal symptoms. Understanding the structure of nicotine polacrilex is crucial for developing effective smoking cessation aids and nicotine replacement therapies.